大鼠胫骨骺板软骨细胞P物质的表达 |
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投稿时间:2001-05-31
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作者 | Author | 单位 | Address | E-Mail |
李靖 |
LI Jing |
第四军医大学西京医院全军骨科研究所,陕西西安710033 |
Xijing Hospital of the 4th Military University Shanxi Xian,710033 |
|
王全平 |
WANG Quan ping |
第四军医大学西京医院全军骨科研究所,陕西西安710033 |
Xijing Hospital of the 4th Military University Shanxi Xian,710033 |
|
陶惠人 |
TAO Hui ren |
第四军医大学西京医院全军骨科研究所,陕西西安710033 |
Xijing Hospital of the 4th Military University Shanxi Xian,710033 |
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吕荣 |
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第四军医大学西京医院全军骨科研究所,陕西西安710033 |
Xijing Hospital of the 4th Military University Shanxi Xian,710033 |
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范宏斌 |
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第四军医大学西京医院全军骨科研究所,陕西西安710033 |
Xijing Hospital of the 4th Military University Shanxi Xian,710033 |
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王哲 |
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第四军医大学西京医院全军骨科研究所,陕西西安710033 |
Xijing Hospital of the 4th Military University Shanxi Xian,710033 |
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期刊信息:《中国骨伤》2002年,第15卷,第11期,第664-665页 |
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
基金项目: |
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中文摘要:
目的:研究P物质(SP)在大鼠胫骨骺板软骨细胞中的表达及其在长骨纵向生长中的意义。
方法:应用免疫组化技术检测8周龄大鼠胫骨骺板不同组织学层次软骨细胞的SP表达状况。
结果:骺板静止及增殖期软骨细胞未见SP免疫阳性染色,肥大区及钙化区软骨细胞可见SP免疫组化阳性染色。
结论:骺板肥大区及钙化区软骨细胞可以表达SP,提示SP在长骨的纵向生长中可能起调节作用。 |
【关键词】胫骨 骺软骨 免疫组织化学 |
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Expression of substances P in chondrocyte of rat’s tibia epiphyseal plate |
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ABSTRACT
Objective:To observe the expression of substances P(SP)in chondrocyte of rats tibia epiphyseal plate and its significance in longitudinal growth of long bone
Methods:To detect the expression of substances P(SP) in chondrocyte of 8 weeks old rats tibia epiphyseal plate of different histology level with immunohistochemical technique.
Results:The expression of SP were positive in maturing and calcifying chondrocyte and negative in static and proliferative phase.
Conclusion: SP were expressed in hypertrophic chondrocytes of epiphyseal plate.SP may regulate the bone modeling,espically in longitudinal growth of long bone. |
KEY WORDS Tibia Epiphyseal cartilage Immunohistochemistry |
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引用本文,请按以下格式著录参考文献: |
中文格式: | 李靖,王全平,陶惠人,吕荣,范宏斌,王哲.大鼠胫骨骺板软骨细胞P物质的表达[J].中国骨伤,2002,15(11):664~665 |
英文格式: | LI Jing,WANG Quan ping,TAO Hui ren.Expression of substances P in chondrocyte of rat’s tibia epiphyseal plate[J].zhongguo gu shang / China J Orthop Trauma ,2002,15(11):664~665 |
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