| bBMP-胶原-珊瑚复合人工骨修复股骨头骨缺损的生物力学研究 |
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投稿时间：1999-09-22 修订日期：2000-01-12
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| 作者 | Author | 单位 | Address | E-Mail |
| 徐小良 |
XU Xiao liang |
西安医科大学第二附属医院,陕西西安710004 |
The Second Affiliated Hospital of Xi′an Medical University Shanxi Xi′an,710004 |
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| 王坤正 |
WANG Kun zheng |
西安医科大学第二附属医院,陕西西安710004 |
The Second Affiliated Hospital of Xi′an Medical University Shanxi Xi′an,710004 |
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| 杨增华 |
YANG Zeng hua |
西安医科大学第二附属医院,陕西西安710004 |
The Second Affiliated Hospital of Xi′an Medical University Shanxi Xi′an,710004 |
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| 牒军 |
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西安医科大学第二附属医院,陕西西安710004 |
The Second Affiliated Hospital of Xi′an Medical University Shanxi Xi′an,710004 |
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| 党晓谦 |
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西安医科大学第二附属医院,陕西西安710004 |
The Second Affiliated Hospital of Xi′an Medical University Shanxi Xi′an,710004 |
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| 阎宏伟 |
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西安医科大学第二附属医院,陕西西安710004 |
The Second Affiliated Hospital of Xi′an Medical University Shanxi Xi′an,710004 |
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| 李旭东 |
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西安医科大学第二附属医院,陕西西安710004 |
The Second Affiliated Hospital of Xi′an Medical University Shanxi Xi′an,710004 |
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| 张开放 |
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西安医科大学第二附属医院,陕西西安710004 |
The Second Affiliated Hospital of Xi′an Medical University Shanxi Xi′an,710004 |
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| 陈君长 |
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西安医科大学第二附属医院,陕西西安710004 |
The Second Affiliated Hospital of Xi′an Medical University Shanxi Xi′an,710004 |
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| 期刊信息：《中国骨伤》2001年，第14卷，第1期，第17-19页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
| 基金项目: |
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中文摘要:
目的:研究用bBMP胶原珊瑚复合人工骨修复股骨头骨缺损的生物力学变化。
方法:建立狗双侧股骨头内骨缺损模型, 4周后分为5组:复合人工骨组、肌骨瓣组、单纯珊瑚组、对照组、正常组。植入后16周行病理学检查及生物力学测定。
结果:人工骨组的骨缺损消失或显著变小, 与对照组相比有显著性差异。人工骨组软骨下骨的抗压强度及弹性模量较对照组及正常组低。
结论:复合人工骨有较强的修复股骨头骨缺损的能力, 但不能改善软骨下骨的生物力学性能。 |
| 【关键词】股骨头坏死 骨质再生 生物力学 植入物,人工 |
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| A biomechanical study of bBMP-collagen-coral composited bone substitute for the treatment of canine bone defect of the femoral head |
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ABSTRACT
Objective:To study the biomechanical changes of bBMP collagen coral composited bone substitute for the treatment of canine bone defect of the femoral head.
Methods:Canine bone defect of bilateral femoral head was established.After 4 weeks,they were divided into 5 groups:Ⅰ.composited bone substitute group;Ⅱ.Muscle pedicle bone group;Ⅲ.simple coral group;Ⅳ.control group;Ⅴ.normal group.Pathological and biomechanical changes of femoral head were studied at 16 weeks after treatment.
Results:Compared with control group,the bone defect of group I was much smaller.The maximum stress and modulus of elasticity of subchondral bone of group I were lower than that of group V and group Ⅳ.
Conclusion:The composited bone substitute possesses a superior property for repairing bone defect of femoral head,but it is unable to improve the biomechanical property of subchondral bone of femoral head. |
| KEY WORDS Femur head necrosis Osteosis Biomechanics Implants artificial |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 徐小良,王坤正,杨增华,牒军,党晓谦,阎宏伟,李旭东,张开放,陈君长.bBMP-胶原-珊瑚复合人工骨修复股骨头骨缺损的生物力学研究[J].中国骨伤,2001,14(1):17~19 |
| 英文格式: | XU Xiao liang,WANG Kun zheng,YANG Zeng hua.A biomechanical study of bBMP-collagen-coral composited bone substitute for the treatment of canine bone defect of the femoral head[J].zhongguo gu shang / China J Orthop Trauma ,2001,14(1):17~19 |
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