骨松Ⅱ号对去卵巢兔骨代谢影响的骨计量学研究
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作者Author单位AddressE-Mail
史炜镔 Shi Weibi 上海第二医科大学上海市伤骨科研究所,200025 Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025  
杜宁 Du Ning 上海第二医科大学上海市伤骨科研究所,200025 Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025  
符诗聪 Fu Shicong 上海第二医科大学上海市伤骨科研究所,200025 Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025  
王济纬 上海第二医科大学上海市伤骨科研究所,200025 Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025  
曲克服 上海第二医科大学上海市伤骨科研究所,200025 Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025  
李国衡 上海第二医科大学上海市伤骨科研究所,200025 Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025  
期刊信息:《中国骨伤》1997年,第10卷,第3期,第11-14页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz
基金项目:
中文摘要:运用骨计量学观察了中药膏极Ⅱ号对兔切除卵巢诱导的骨质疏松症实验模型的影响,并与尼尔雌醇进行对照。结果显示:骨松Ⅱ号组与尼尔雌醇组在BV/TV、OV/BV、OBI、dLs/BS和BFR(T)等参数方面明显高于造模组和/或正常对照组,骨松Ⅱ号组OV/BV、OB%以及OBI等参数较尼尔雌醇级明显升高。提示:骨松Ⅱ号能增加成骨细胞数量,以产生较多骨质,使骨疏松症模型兔的骨代谢恢复正平衡,达到防治骨质疏松症的目的,其作用一定程度上优于尼尔雌醇。
【关键词】骨松Ⅱ号  卵巢摘除  骨代谢  骨计量学
 
Histomorphometric Study on the Effect of Gusong Ⅱ on Bong Turnover in Ovariectomized Rabbits
ABSTRACT  The effects of gusong Ⅱ on experimental postmenopausal osteoporosis in ovariectomized New Zealand white rabbits were assessed histomorpphometrically and compared with that of nylestriol.The results demonstrated that BV/TV, OBI, dLs/BS and BFR increased in both group A (OVX- Gusong Ⅱ) and group D (OVX-nylestriol ) as compared with group B (OVX) and/or group C (Sham). Group A showed a significant increase of OV/13V,OB% and UBI as compared with group D. It indicated that Gusong Ⅱ can stimulate the recruitment and/or proliferation of osteoblasts to produce more bone matrix,converting the bone turnover of OVX rabbits to a positive balance. This effect may be superior to that of nylestriol to some extent.
KEY WORDS  Chinese herb Gusong Ⅱ  Ovariectomy  New Zealand white rabbit  Bone histomorphometry
 
引用本文,请按以下格式著录参考文献:
中文格式:史炜镔,杜宁,符诗聪,王济纬,曲克服,李国衡.骨松Ⅱ号对去卵巢兔骨代谢影响的骨计量学研究[J].中国骨伤,1997,10(3):11~14
英文格式:Shi Weibi,Du Ning,Fu Shicong.Histomorphometric Study on the Effect of Gusong Ⅱ on Bong Turnover in Ovariectomized Rabbits[J].zhongguo gu shang / China J Orthop Trauma ,1997,10(3):11~14
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