| 坚硬接骨板固定后局部骨质疏松的骨组织形态计量学的实验研究 |
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投稿时间：1994-09-01
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| 期刊信息：《中国骨伤》1996年，第9卷，第1期，第7-8页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
| 基金项目: |
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| 中文摘要:本实验通过骨组织形态计量学的方法,对家兔完整胫骨坚硬接骨板内固定后局部骨组织的变化进行了研究,实验家兔随机分为1、2、3、4组和空白对照组,固定时间为6.8.10和12周。对不脱钙骨组织切片在纵切面和横切面上进行普通光和莹光分析测量。结果发现：坚硬接骨板内固定后六周时固定段骨即出现骨质疏松,发生在哈佛氏系统的骨丢失,10周后骨内膜表面出现骨吸收、骨髓腔增大,两个表面的骨重建单位的负平衡使固定段皮质骨疏松变薄,特别是在钢板下。 |
| 【关键词】内固定 骨质疏松 骨重建 |
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| Experimental study on local osteoporosis secondary to rigid plate internal fixation with bone histomor-phometry |
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| ABSTRACT Through bone histomorphometrical method, local bone changes of rabbit intact tibia after rigid plate internal fixation was studied. Experimental rabbits were divided into 1,2,3,4 and blank control groups in random,with fixation time in 6,8,10 and 12 weeks respeclively. Histomorphometrical and tetracycline fluorescence measurement were undertaken in non-decalcified bone tissue sections longitudinally and transversely.The results revealed that there was osteoporosis appeered at 6 weeks in rigid fixating segment. Bone lossing happened at Havei s system. bone absorption revealed after lOweeks on endosteal surface and enlargewent of bone marrow. Osteoporosis and thinning of the cortex on fixating segment.especially under steel plate happened due to negative balance of remodeling process of the two surface of the bone. |
| KEY WORDS Internal fixation Osteoporosis Bone remodeling |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 武宇赤,娄思权,党耕町.坚硬接骨板固定后局部骨质疏松的骨组织形态计量学的实验研究[J].中国骨伤,1996,9(1):7~8 |
| 英文格式: | Wu Yu-shi,Lou Si-quan,Dang Geng-ding.Experimental study on local osteoporosis secondary to rigid plate internal fixation with bone histomor-phometry[J].zhongguo gu shang / China J Orthop Trauma ,1996,9(1):7~8 |
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