| 骨痂中多核巨细胞与破骨细胞的组织学及超微结构观察 |
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投稿时间：1994-02-28 修订日期：1994-08-16
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| 作者 | Author | 单位 | Address | E-Mail |
| 常超英 |
Chang Chaoying |
中国中医研究院骨伤科研究所 |
Institute of Orthopaedics and Traumatology,China Academy of TCM,Beijing 100700
Institute of Orthopaedics and Traumatology Guiyang College of TCM, Guiyang 350001 |
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| 夏志道 |
Xia Zhidao |
同济医科大学附属协和医院 |
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| 房世源 |
Fang Shiyuan |
中国中医研究院骨伤科研究所 |
Institute of Orthopaedics and Traumatology,China Academy of TCM,Beijing 100700
Institute of Orthopaedics and Traumatology Guiyang College of TCM, Guiyang 350001 |
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| 孙树椿 |
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中国中医研究院骨伤科研究所 |
Institute of Orthopaedics and Traumatology,China Academy of TCM,Beijing 100700
Institute of Orthopaedics and Traumatology Guiyang College of TCM, Guiyang 350001 |
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| 王来鸿 |
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中国中医研究院骨伤科研究所 |
Institute of Orthopaedics and Traumatology,China Academy of TCM,Beijing 100700
Institute of Orthopaedics and Traumatology Guiyang College of TCM, Guiyang 350001 |
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| 吴非 |
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贵阳中医学院骨伤科研究所 |
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| 时光达 |
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贵阳中医学院骨伤科研究所 |
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| 期刊信息：《中国骨伤》1995年，第8卷，第1期，第8-9页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
| 基金项目: |
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| 中文摘要:本文通过光镜与透射电镜对家兔桡骨标准分析模型骨痂内多核巨细胞与破骨细胞形态进行了观察。观察显示,两种细胞均参与骨吸收,但多核细胞主要在分析早期吸收死骨和骨碎屑,吸收方式包括吞噬和细胞外降解；破骨细胞主要吸收钙化软骨骨痂和新生骨小粱,通过细胞外吸收方式完成骨痂改建。作者认为,多核巨细胞表面的丝状伪足和破骨细胞表面的皱折缘与骨矿物质细胞外降解有关,但其降解机理的差别尚有待揭示。 |
| 【关键词】骨痂 组织学 超微结构 |
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| Multinclear giant cells and osteoclasts in callus -histological and ultrastructural observation |
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| ABSTRACT The morphology of multinuclear giant cells (MGC) and osteoclasts (Oc) in rabbit's radius callus had been observed by light microscopy and transmission electron microscopy.It showed that both MGC and Oc participated in bone resorption, but MGCmainly resorbed dead bone and bone chips through phagocytosis and extracellular degradation at the early stage of fracturehealing, and Oc mostly resorbed calcified cartilaginous callus and new formed trabecular bone by extracellular resorption to accomplish the remodeling of callus. It is suggested that the filopods on the surface of MGC and ruffled border on the surface of Oc are closely related to extracellular degrdation of bone mineral. Their difference in the mechanism of degradation is waiting or further study. |
| KEY WORDS Callus Histology Ultrastructure |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 常超英,夏志道,房世源,孙树椿,王来鸿,吴非,时光达.骨痂中多核巨细胞与破骨细胞的组织学及超微结构观察[J].中国骨伤,1995,8(1):8~9 |
| 英文格式: | Chang Chaoying,Xia Zhidao,Fang Shiyuan.Multinclear giant cells and osteoclasts in callus -histological and ultrastructural observation[J].zhongguo gu shang / China J Orthop Trauma ,1995,8(1):8~9 |
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