| 骨折愈合中的软骨骨痂──形态学演变及超微结构观察 |
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| 期刊信息：《中国骨伤》1994年，第7卷，第6期，第10-12页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
| 基金项目: |
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| 中文摘要:通过光镜下不脱钙骨组织学、组织化学和透射电镜对雄性兔桡骨标准缺损骨折模型愈合中软骨骨痂的形成、演变及超微结构进行了观察,结果显示：软骨骨痂由骨折后进入断端间的肉芽组织分化而成,其形成和改建并不完全相同于骺板软骨内化骨。电镜下,骨痂内软骨细胞可分为5个发育阶段：成软骨细胞、软骨细胞、肥大软骨细胞、变性软骨细胞和残存软骨细胞。我们认为1)软骨骨痂由断端周围组织内的间充质细胞分化而成；2)在改建过程中,软骨骨痂能直接形成骨小梁,我们支持肥大软骨细胞能转化为骨细胞的假说；3)软骨骨痂对骨折愈合有重要的作用,能早期填充骨缺损,联接断端,是骨折在重力负载下完成愈合的基础组织之一。 |
| 【关键词】软骨骨痂 骨折愈合 形态学 |
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| Cartilage callus in bone healing |
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| ABSTRACT Through light microscopic non-decalcified bone histological, histochemical and electron microscopic observations on formation,evolution and ultrstructure of cartilage callus of rabbit radial bone fracture standard defect model during healing process, the results showed that the cartilage callus comes from differentiation of granular tissue of the fracture ends,its formation and reconstruction did not completely similar with ossification in the epiphyseal chondrium.There are five evolutionary stages of cartilage callus cells,the callus under electron microscopic findings,i. e chondroblasts,chondrocytes hypertrophic chonocytes,degenerative chonrocytes and remnant chondrocytes.We realized that 1)the chondrial callus is differentiated from interstitial cells surrounding the fracture end,2)during reconstruction process,chondrial callus can directly form bone trabeculae.We support the hypothesis that hypertrophied chonocytes.can transfer to bone cells, 3)chondrial callus bears important action during healing process. it can fulfil bone defect in the early stage, connect fracture ends, the fracture healing process is completed under the burden of gravity. |
| KEY WORDS Cartilage callus Fracture healing Morphology |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 夏志道,常超英,房世源,孙树椿,王来鸿,吴非.骨折愈合中的软骨骨痂──形态学演变及超微结构观察[J].中国骨伤,1994,7(6):10~12 |
| 英文格式: | Xia Zhidao,Chang Chaoying,Fang Shiyuan,Sun Shuchun,Wang laihong,Wu Fei.Cartilage callus in bone healing[J].zhongguo gu shang / China J Orthop Trauma ,1994,7(6):10~12 |
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